Validation of a novel method for measuring intra-abdominal pressure and gastric residual volume in critically ill patients

Page hits: 2759, File downloaded: 420

Download file

Download this file

Open in browser

Open this file in your browser


Johan Van Stappen, Chiara Pigozzi, Robert Tepaske, Niels Van Regenmortel, Inneke De laet, Karen Schoonheydt, Hilde Dits, Paolo Severgnini, Derek J. Roberts, Manu LNG Malbrain



Gastric residual volume (GRV) can be measured in a variety of ways in critically ill patients, most often, the nasogastric tube is disconnected and the GRV is aspirated via a 60 mL syringe. Bladder pressure (IBP) measurement is the gold standard for intra-abdominal pressure (IAP) estimation. This study will look at the validation of a novel method combining measurement of GRV and estimation of IAP via intra-gastric pressure (IGP).


In total 135 paired IAP and 146 paired GRV measurements were performed in 37 mechanically ventilated ICU patients. The IAP was estimated via the bladder (i.e. IBP) using the FoleyManometer and via the stomach (i.e. IGP) with the new device. The GRV was measured with the new device (GRVprototype) and via the classic method (GRVclassic). The devices were provided by Holtech Medical (Charlottenlund, Denmark) and data were retrospectively analysed.


The number of paired measurements in each patient was 4 ± 1. The mean IBP was 10.7 ± 4.1 and mean IGP was 11.6 ± 4.1 mm Hg. Correlation between the IBP and IGP was significant, however moderate (R2 = 0.51). Analysis according to Bland and Altman showed a bias and precision of 0.8 and 2.7 mm Hg respectively, however the limits of agreement (LA) were large and ranged from −4.5 to 6.1 mm Hg. Changes in IGP correlated well with changes in IBP. The median GRVprototype was 80 mL (0–1050) and equal to the median GRVclassic of 80 mL (0−1250). Correlation between the 2 methods was excellent (R2 = 0.89). Analysis according to Bland and Altman showed a bias and precision of -0.8 and 52.3 mL respectively and the LA ranged from –103 to 102 mL. Changes in GRVclassic correlated well with changes in GRVprototype.


The results of this multicentre pilot study show that GRV can be measured with the new device. Furthermore this allows simultaneous screening for intra-abdominal hypertension with IAP estimation via IGP.

Leave a comment

Please login to leave a comment.

Social Media

  like us on Facebook

  follow us on Twitter

  join Discussion group

  join us on Linkedin

  newsletter sign up

  post on the blog