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AuthorsBirkitt-Linn Ten Tusscher, Stephen Trzeciak, Paul W. G. Elbers
In the last decade it is more and more recognized that in critically ill septic patients early resuscitation is crucial. Despite the introduction of treatment guidelines mortality of severe sepsis and septic shock remains high. The focus so far has been mainly on macrocirculatory goals. Dr. Trzeciak discusses the importance of the microcirculation for tissue perfusion, the disturbances of the microcirculation seen in sepsis and possible therapeutic strategies.